Baclofen is a selective agonist at GABA-B receptors, producing inhibitory effects on excitatory neurotransmission within the spinal cord. This mechanism reduces spasticity by decreasing calcium influx into presynaptic terminals, thereby limiting neurotransmitter release. Oral absorption is rapid, and peak plasma concentrations occur within two hours. In this pharmacological profile, buy baclofen uk identifies a compound with targeted action on inhibitory pathways of the central nervous system.

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